Adipogen/Adiponectin (mouse) ELISA Kit/AG45A0004YEKKI01/96 wells

Specifications&Handling:

ProductData
Synonyms	ACRP30;AdipoQ;apM1;GBP28;AdipocyteComplementRelatedProteinof30kDa
Properties
ApplicationSet	QuantitativeELISA
Specificity	Detectsmouseadiponectin.Doesnotcross-reactwithhumanadiponectin,ratadiponectin,mouseresistin,mouseRELM-βormouseleptin.
Crossreactivity	Mouse
Quantity	1x96wells 2x96wells(TwinPlex)
Sensitivity	50pg/ml
Range	0.125to8ng/ml
SampleType	CellCultureSupernatant,Plasma,Serum
AssayType	Sandwich
DetectionType	Colorimetric
ProductType	Kit
ShippingandHandling
Shipping	BLUEICE
ShortTermStorage	+4°C
LongTermStorage	+4°C
HandlingAdvice	Afterstandardreconstitution,preparealiquotsandstoreat-20°C.Avoidfreeze/thawcycles.Plateandreagentsshouldreachroomtemperaturebeforeuse.
Use/Stability	12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox.
Documents
Manual	Download
MSDS	Download
RelatedProducts
Adiponectin(mouse)(rec.)(BULK) Adiponectin(human)ELISAKit

Description:

Adiponectin[ACRP30;AdipoQ]isapromisingbioMarkerofinsulinresistanceandtype2diabetesmellitus(T2DM)butalsoasapotentialtargetformanagementofthemetabolicsyndrome.Itisaveryrobustmarkerthatisnotpronetodegradationoracuteinflammatorychallenges,ispresentinrelativelyhighconcentrationsintheperipheralcirculation,andcanbecollectedbyavarietyofmethods.Thebenefitsofusingadiponectinassaysinclinicalsettingsinclude,(a)predictionofriskofdiabetesandmetabolicstatusand(b)providingatooltomonitormetabolicimprovements.Adiponectinexertsanti-atherogenicandanti-inflammatorypropertiesandmaybeimportantasabiomarkerforobesity-relatedcardiovasculardisease(CVD).NewfindingsshowedurinaryadiponectinexcretionasanindependentnewbiomarkerofmicrovascularandmacrovasculardamageinT2DMandsuggesteditasaverypromisingtoolforearlycardiovasculardiseaseriskassessment.Adiponectinserumlevelwasalsodescribedasagoodbiomarkerofcolorectaladenoma,thisbeingrelatedtothepositivecorrelationbetweenobesityandincreasedriskofcanceratvarioussites(colorectal,breast,prostateandendometrium).