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| Synonyms | Monoclonal DLD antibody, Anti-DLD antibody, Dihydrolipoamide Dehydrogenase antibody, DLDH antibody, E3 antibody, GCSL antibody, LAD antibody, PHE3 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | FC, WB |
| Immunogen | DLD antibody was raised in mouse using a full length recombinant protein of human DLD (NP_000099) produced in HEK293T cells, as the immunogen. |
| Host | Mouse |
|---|---|
| Clone | 5G7 |
| Isotype | IgG1 |
| Method of Purification | DLD antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Usage Recommendations | FC: 1:100, WB: 1:2000 |
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| Biological Significance | DLD is the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. |
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