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Cedarlane/Anti-human synaptophysin, Purified, (clone SP15), (Mouse IgM)/CL2702AP/200ug188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Cedarlane/Anti-human synaptophysin, Purified, (clone SP15), (Mouse IgM)/CL2702AP/200ug

Description
Synaptophysinisa38KDasynapticvesicle(SV)glycoproteincontainingfourtransmembranedomains.ItispresentinSVsoftheneuroendocrinesystem,brain,spinalcord,retina,adrenalmedullaandatneuromuscularjunctions.synaptophysinactsasamakerforneuroedocrinetumoursandhasbeenusedtostudythedistributionofsynapseswithinthebrainduetoitsubiquityattheseregions.
Althoughtheexactfunctionofsynaptophysinisstillunknown,severallinesofevidencesuggestitmayhavemultipleimportantrolesinSVexoandendocytosis.TheseincluderegulationofSNAREassembly,fusionporeformationinitiatingneurotransmitterreleaseandactivationofSVendocytosis.Additionally,itisthoughtthatsynaptophysinmayhaveanimportantroleinSVbiogenesis.______________________________________________________________________________________________________
ImmunofluorescenceAnalysis

PurifiedAnti-HumanSynaptophysin(CL2702AP)stainingofparaformaldehyde-fixedparaffin-embeddedhumancerebellumsectionsat200x(A)and400x(B)magnificationwithDAPIcounterstain.(Mouseanti-humanSynaptophysin(CL2702AP)1:500;AlexaFluor488Goatanti-mouse 1:500 (MolecularProbes)andNormalGoatSerum(blocking))
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