产品资料

Rockland/AFAP1L Antibody/600-401-X78/100 µg

AFAP1LAntibodyProperties

Description

Anti-AFAP1L(RABBIT)Antibody-600-401-X78

Host

Rabbit

TargetSpecies

Human

KnownCrossReactivity

Human,mouse

Clonality

Polyclonal

Application

ELISA:1:10,000
IFMicroscopy:20µg/mL
WesternBlot:1µg/mL
OtherDilution:Immunocytochemistry:5µg/mL

PhysicalState

Liquid(sterilefiltered)

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Concentration

1mg/mLbyUVabsorbanceat280nm

Buffer

0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2

Preservative

0.02%(w/v)SodiumAzide

StABIlizer

None

GeneName

AFAP1L1

RelevantLinks

UniProtKB-Q8TED9
GeneID-134265
NCBI-NP_689619

AFAP1LAntibodyDescription

Background

Theactinfilament-associatedprotein1(AFAP1)-like1proteinisoneofthreemembersintheAFAP1familyofadaptorproteins.LikeAFAP1,AFAP1L1isanactinbindingproteinthathasaroleinactinCytoskeletonarrangement,butAFAP1L1isthoughttohaveauniquefunctiondistinctfromAFAP1.AFAP1L1colocalizeswithcortactinandlocalizestoinvadosomes,highlydynamic,actin-richadhesionstructuresharboringmetalloproteases,suggestingthatAFAP1L1affectsinvadosomeformation(1,4).RecentreportssuggestthatAFAP1L1canbeusedasaprognosticMarkerforspindlecellsarcomas.

Synonyms

AFAP1LAntibody,Actinfilament-associatedprotein1-like1,AFAP1-likeprotein1

Immunogen

Anti-AFAP1L1antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha19aminoacidsyntheticpeptideneartheN-terminusofhumanAFAP1L1.

ImmunogenType

Peptide

StorageCondition

Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-AFAP1LAntibodyhasbeentestedforuseinELISA,WesternBlotting,ImmunocytochemistryandImmunofluorescence.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately86kDainWesternBlotsofspecificcelllysatesandtissues.

Purity/Specifity

Anti-AFAP1LAntibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.AtleastfourisoformsofAFAP1L1areknowntoexist.Thisantibodyispredictedtonotcross-reactwithotherAFAPfamilymembers.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

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Rockland/AFAP1L Antibody/600-401-X78/100 µg

AFAP1LAntibodyProperties

AFAP1LAntibodyDescription