产品资料

Rockland/APPBP2 Antibody/600-401-Y52/100 µg

APPBP2AntibodyProperties

Description

Anti-APPBP2(RABBIT)Antibody-600-401-Y52

Host

Rabbit

TargetSpecies

Human

KnownCrossReactivity

Human,mouse,rat

Clonality

Polyclonal

Application

ELISA:1:5000-1:10000
IFMicroscopy:20µg/mL
WesternBlot:0.5-1µg/mL
Immunohistochemistry:5µg/mL

PhysicalState

Liquid(sterilefiltered)

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Concentration

1mg/mLbyUVabsorbanceat280nm

Buffer

0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2

Preservative

0.02%(w/v)SodiumAzide

StABIlizer

None

GeneName

APPBP2

RelevantLinks

UniProtKB-Q92624
GeneID-10513
NCBI-NP_006371

APPBP2AntibodyDescription

Background

Theamyloidbetaprecursorprotein(cytoplasmictail)bindingprotein2(APPBP2),alsoknownasPAT1,interactswithmicrotubulesandisfunctionallyassociatedwithbeta-amyloidprecursorproteintransportand/orprocessing(1).Thebeta-amyloidprecursorproteinisacellsurfaceproteinwithsignal-transducingproperties,anditisthoughttoplayaroleinthepathogenesisofAlzheimer"sdisease(2).APPBP2hasbeenfoundtobehighlyexpressedinbreastcancer(3).

Synonyms

APPBP2Antibody,PAT1,APP-BP2,HS.84084,KIAA0228,PAT1,Amyloidprotein-bindingprotein2,Amyloidbetaprecursorprotein-bindingprotein2

Immunogen

Anti-APPBP2antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithan18aminoacidpeptideneartheC-terminusofhumanAPPBP2.

ImmunogenType

Peptide

StorageCondition

Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-APPBP2AntibodyhasbeentestedforuseinELISA,WesternBlotting,ImmunohistochemistryandImmunofluorescence.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately67kDainWesternBlotsofspecificcelllysatesandtissues.

Purity/Specifity

Anti-APPBP2antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.APPBP2antibodyishuman,mouseandratreactive.AtleasttwoisoformsofAPPBP2areknowntoexist;thisantibodywilldetectbothisoforms.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

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Rockland/APPBP2 Antibody/600-401-Y52/100 µg

APPBP2AntibodyProperties

APPBP2AntibodyDescription