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Lee Biosolutions/Haptoglobin (Hp)/336-11-1/1 mg

Description
ProductNameHaptoglobin
SourceCanineSerum
CatalogueNumber336-11
Purity>90%(SDS-PAGE)
FormLiquid
Protein0.5-2.5mg/mL(BradfordProteinAssay)
FormLiquidin10mMsodiumphosphate,150mMsodiumchloridewith0.05%sodiumazide,pH7.2.
Recertification2years
Storage-20°C
Applications
Controls/Calibrators/StandardsImmunoassaysClinicalChemistryLifeScienceVeterinary
Overview

.

Haptoglobin(frequentlyabbreviatedasHp)isaproteininthebloodplasmathatbindsfreehemoglobinreleasedfromerythrocyteswithhighaffinityandtherebyinhibitsitsoxidativeactivity.Thehaptoglobin-hemoglobincomplexwillthenberemovedbythereticuloendothelialsystem(mostlythespleen).Haptoglobinisaserumproteinthatconsistsoftwoalphaandtwobetachainsconnectedbydisulfidebridges.Itactsasahemoglobinscavengerandhasbeenassociatedwithproteaseinhibitoryactivity.CANINEHAPTOGLOBINisapositiveacutephasereactant,thelevelsofwhichincreasesignificantlyinDOG(S)inresponsetoinflammation,tissueinjuryordisease.

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