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Innovative Research/Human Granzyme B ELISA Kit/IRKTAH5125/1 Ea

ProductDescription

HumanGranzymeBELISAKit-1Kit(96Wells)
OurHumanGranzymeBELISAKitisasandwichELISAintendedforthequantitativedeterminationofhumanGranzymeBincellculturesupernates,serumandplasma(heparin,EDTA).

GranzymeBisaserineproteasethatinhumansisencodedbytheGZMBgene.GranzymeBisexpressedbycytotoxicTlymphocytes(CTL)andnaturalkiller(NK)cells.CTLandNKcellssharetheremarkableABIlitytorecognizespecificinfectedtargetcells.Theyarethoughttoprotecttheirhostbyinducingapoptosisofcellsthatbearontheirsurface"nonself"antigens,usuallypeptidesorproteinsresultingfrominfectionbyintracellularpathogens.TheproteinencodedbythisgeneiscrucialfortherapidinductionoftargetcellapoptosisbyCTLincell-mediatedimmuneresponse.

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