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Prosci/ApoE3 Recombinant Protein/40-136/0.1 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Prosci/ApoE3 Recombinant Protein/40-136/0.1 mg

Specifications

SPECIES:Human
SOURCESPECIES:E.coli
SEQUENCE:MKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH
TESTEDAPPLICATIONS:

Properties

PURITY:Greaterthan90%bySDS-PAGEgelandHPLCanalyses.

Endotoxinlevelislessthan0.1ngperμg(1EU/μg).
PHYSICALSTATE:Lyophilized
STORAGECONDITIONS:ThelyophilizedApoE3recombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedApoE3isstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingApoE3recombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature.

AdditionalInfo

ALTERNATENAMES:AD2,LPG,LDLCQ5,ApolipoproteinE,Apo-E
ACCESSIONNO.:NP_000032.1
PROTEINGINO.:4557325

Background

ApoE3belongstoagroupofproteinsthatbindreversIBLywithlipoproteinandplayanimportantroleinlipidmetabolism.Inadditiontofacilitatingsolublizationoflipids,theseproteinshelptomaintainthestructuralintegrityoflipoproteins,serveasligandsforlipoproteinreceptors,andregulatetheactivityofenzymesinvolvedinlipidmetabolism.SignificantquantitiesofApoEareproducedinliverandbrainandtosomeextentinalmosteveryorgan.ApoEexistsinthreemajorisoforms;E2,E3,andE4,whichdifferfromoneanotherbyasingleamino-acidsubstitution.E3isthemostcommonisoformandispresentin40-90%ofthepopulation.RecombinanthumanApoE3isa34.4kDaproteincontaining300aminoacidresidues.
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