| CatalogNumber: 21218 |
| GeneSymbol: GRB7 |
| Description: Anti-GRB7RabbitPolyclonalAntibody |
| Background: Grb7isanadaptorproteinthatinteractswithepidermalgrowthfactorreceptor(EGFR)andephrinreceptors.Itplaysaroleintheintegrinsignalingpathwayandcellmigrationbybindingwithfocaladhesionkinase(FAK).Grb7geneiscommonlyco-amplified(presentinexcesscopies)inbreastcancers.Grb7isover-expressedintesticulargermcelltumors,esophagealcancers,andgastriccancers.Therearecluesthatitinvolvedincellmigrationandmetastaticprogressionofhumanesophagealcarcinomas. |
| Immunogen: AsyntheticpeptidefromtheC-terminusofGRB7protein,humanorigin. |
| Applications: ELISA,WB,IHC |
| RecommendedDilutions: ELISA:1:1000-1:5000WB:1:250-1:1000IHC:1:50-1:100 |
| Concentration: 0.5mg/ml |
| Host: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purifiedfromserum |
| Storagebuffer: |
| Preservative: no |
| Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
| SpeciesReactivity: Anti-GRB7rabbitpolyclonalantibodyrecognizesGRB7fromvertebrates. |
| StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles. |
DownloadDatasheet: ![]() |
| Westernblot: |
![]() | WesternblotanalysisofGRB7proteins.Whole-celllysateofMEFcellswasblottedwithanti-GRB7polyclonalantibody(Cat.#26071). |
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