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| Overview | |
| Catalog # | bs-2066R-A680 |
| Product Name | GSK-3 Beta(Ser9) Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated |
| Applications | IF(IHC-P), IF(IHC-F), IF(ICC) |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | ALEXA FLUOR® 680 |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human GSK-3 Beta around the phosphorylation site of Ser9 |
| Modification Site | Ser9 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| Storage Condition | Store at 4°C for 12 months. |
| Target | |
| Gene ID | 2932 |
| Swiss Prot | P49841 |
| Subcellular location | Cytoplasm, Nucleus, Cell membrane |
| Synonyms | Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B; GSK3B |
| Background | The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| Application Dilution | |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
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