产品资料

academy biomed/[A01] Goat Anti-Human Albumin Polyclonal Antibody/1.0 mg/AL10A-G1b

Host Species:	Goat
Concentration:	1 mg/ml (OD 1.35 / 280 nm)
Antigen:	Human albumin
Purification:	Affinity purified
Buffer:	75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02% NaN3, pH 7.2
Specificity	Specifically binds to human albumin. Dilution for immunoblot & ELISA range: 1,000 to 80,000. Centrifuge before use.
Use:	The antibody can be used for detection of human albumin in plasma and lipoproteins, immunoassays, immunoblots, enzyme conjugation, or biotinylation.
Storage:	-20°C for long-term storage, 4°C for short- term storage. Aliquot to avoid repeated freezing and thawing.

*These products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.

Importance

Human albumin constitutes around 55% of the protein present in the plasma of normal healthy individuals. It is a single polypeptide chain of 585 amino acids with a molecular weight of 66 kDa.

The functions of human serum albumin include maintaining oncotic pressure; binding substances or drugs; regulating endogenous substances, metabolism; plasma buffer; antioxidant function; maintaining microvascular integrity; anticoagulant effects; inflammatory/anti-inflammatory effects; cell-signaling process. (Nicholson et al., 2000; Evans, 2002) Albumin also has functions that may play a critical role and have a great impact on different types of diseases, including hypo-albumin aemia and peripheral oedema. (Caironi et al. 2009)

Caironi, Pietro, and Luciano Gattinoni. "The clinical use of albumin: the point of view of a specialist in intensive care. " Blood Tranfusion 7.4 (2009): 259-67.

Evans, T. W. "Review Article: Albumin as a Drug-biological Effects of Albumin Unrelated to Oncotic Pressure." Alimentary Pharmacology and Therapeutics 16 (2002): 6-11.

Nicholson, J. P., M. R. Wolmarans, and G. R. Park. "The Role of Albumin in Critical Illness." British Journal of Anaesthesia 85.4 (2000): 599-610.

Citations

[A01]	2007	Kiyota, Akifumi; Matsushita, Taku; Ueoka, Ryuichi (2007): Induction and high density culture of human hepatoblasts from fetal hepatocytes with suppressing transformation. In Biological & Pharmaceutical Bulletin 30 (12), pp. 2308–2311.
[A01]	2006	Clavant, Steven P.; Sastra, Steve A.; Osicka, Tanya M.; Comper, Wayne D. (2006): The analysis and characterisation of immuno-unreactive urinary albumin in healthy volunteers. In Clinical Biochemistry 39 (2), pp. 143–151. DOI: 10.1016/j.clinbiochem.2005.10.013.

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academy biomed/[A01] Goat Anti-Human Albumin Polyclonal Antibody/1.0 mg/AL10A-G1b

Importance

Citations