企业QQ
官方微信
| AlternativeName: | ESR |
| Clone: | h-151 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Syntheticpeptidecorrespondingtothesequenceofhumanestrogenreceptor,conjugatedtoKLH. |
| UniProtID: | P03372 |
| GenBankID: | M12674 |
| Speciesreactivity: | Human,Rat |
| Applications: | ICC,IP,WB |
| RecommendedDilutions/Conditions: | Immunoprecipitation(15µg/ml) WesternBlot(1:250) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| ApplicationNotes: | Detectsabandof~67kDabyWesternblot. |
| PurityDetail: | ProteinGaffinitypurified. |
| Formulation: | Liquid.InPBS,pH7.2,containing50%glyceroland0.09%sodiumazide. |
| Handling: | Avoidfreeze/thawcycles. |
| Shipping: | ShippedonBlueIce |
| LongTermStorage: | -20°C |
| ScientificBackground: | TheEstrogenreceptors(ER),mainlyERalphaandERbeta,aremembersofthenuclearsteroidhormonereceptorfamilyandarecomposedofthreedomains,anN-terminaldomainrequiredformaximaltransactivationfunction(TAF),aDNAbindingdomain,andasteroidbindingdomain.Estrogenhaspleiotropiceffectsonthegrowth,development,andmaintenanceofdiversetissues. |