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Enzolifesciences/TRAIL-R2 (human) monoclonal antibody (DJR2-4)/ALX-804-914-0100/100µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Enzolifesciences/TRAIL-R2 (human) monoclonal antibody (DJR2-4)/ALX-804-914-0100/100µg

ProductSpecification:

AlternativeName:TRAILreceptor2,DR5,Deathreceptor5,KILLER,CD262,Trick2,Ly98,TNFRSF10B,TNF-relatedapoptosis-inducingligandreceptor2,Tumornecrosisfactorreceptorsuperfamilymember10B
 
Clone:DJR2-4
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:RecombinanthumanTRAIL-R2extracellulardomainIgG1Fcfusionprotein.
 
UniProtID:O14763
 
Gene/ProteinIdentifier:8795(EntrezGeneID)
 
Speciesreactivity:Human
 
Applications:FlowCytometry
 
PurityDetail:Affinitypurified.
 
Formulation:Liquid.InPBS,pH7.2,containing0.09%sodiumazide.
 
Shipping:BlueIceNotFrozen
 
LongTermStorage:+4°C
 
ScientificBackground:DR5is55kDamember10BoftheTNFreceptorsuperfamily(TNFRSF10B),alsoknownasTRAIL-R2,TRICK2,KILLER,andCD262.ItbindsthecytotoxicligandTRAILandinducesapoptosis.TheDR5receptorisbroadlyexpressedonavarietyofnormaltissuesandmanytumors.DR5expressionhasbeenreportedtobeupregulatedinhumancellsbyinterferon-α,2-methoxyestrADIol,andpaclitaxel,anddownregulatedbyadenoviralE3proteins.
 
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