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Enzolifesciences/BID monoclonal antibody (5C9)/ADI-AAM-141-E/100µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Enzolifesciences/BID monoclonal antibody (5C9)/ADI-AAM-141-E/100µg

ProductSpecification:

AlternativeName:BH3interactingdomaindeathagoNIST
 
Clone:5C9
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:SyntheticpeptidecorrespondingtoaportionofhumanBID.
 
UniProtID:P55957
 
Speciesreactivity:Human
 
Applications:WB
 
RecommendedDilutions/Conditions:WesternBlot(1-5µg/ml)
Suggesteddilutions/conditionsmaynotbeavailableforallapplications.
Optimalconditionsmustbedeterminedindividuallyforeachapplication.
 
ApplicationNotes:Detectsabandof~24kDabyWesternblot.
 
PurityDetail:ProteinAaffinitypurified.
 
Formulation:Liquid.InPBScontaining50%glycerol.
 
Shipping:ShippedonBlueIce
 
LongTermStorage:-20°C
 
ScientificBackground:BIDisanapproximately22kDaproteinbelongingtotheBcl-2family.BIDisacytosolicproteinthatiscleavedbycaspase-8inresponsetodeathreceptorstimulation.ProteolyticcleavageofBIDresultsintheformationofa15kDafragment,referredtoastBID.tBIDmigratestothemitochondriawhereitaidsinthereleaseofcytochromecandthesubsequentactivationoftheapoptosome.tBIDservesasalinkbetweendeathreceptordependentandmitochondrialmediatedapoptosis.
 
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