| AlternativeName: | 8-iso-ProstaglandinF2α |
| Host: | Rabbit |
| Immunogen: | 8-iso-ProstaglandinF2αconjugatedtoporcinethyroglobulin. |
| Speciesreactivity: | Speciesindependent |
| Applications: | ELISA |
| Formulation: | Liquid.Containssodiumazide. |
| Handling: | Avoidfreeze/thawcycles. |
| Shipping: | ShippedonBlueIce |
| LongTermStorage: | -20°C |
| ScientificBackground: | ProstaglandinF2alpha(PGF2alpha)isformedinavarietyofcellsfromPGH2,whichitselfissynthesizedfromarachidonicacidbytheenzymeprostaglandinsynthetase.PGF2alphaisoftenviewedasanantagonisttoPGE2duetotheiropposingeffectsonvarioustissues.PGF2alphaisapotentbronchoconstrictorandhasbeenimplicatedinasthmaattacks.PGF2alphaisalsoinvolvedinreproductivefunctionsincludingcorpusluteumregulation,uterinecontractions,andspermmotility.Thishasledtoitsuseinterminatingpregnanciesandinducinglaboratterm.HighlevelsofPGF2alphahavealsobeenassociatedwithpreeclampsia. |