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| AlternativeName: | Synaptosomal-associatedprotein25 |
| Host: | Rabbit |
| Immunogen: | SyntheticpeptidecorrespondingtoaportionofmouseSNAP-25.Thesequenceiscompletelyconservedinhuman,chicken,andgoldfish. |
| UniProtID: | P60879 |
| GenBankID: | M22012 |
| Speciesreactivity: | Mouse,Rat Xenopus |
| Applications: | IF,IHC,WB |
| RecommendedDilutions/Conditions: | WesternBlot(1µg/ml,colorimetric) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| ApplicationNotes: | Detectsabandof~25kDabyWesternblot. |
| PurityDetail: | ProteinAaffinitypurified. |
| Formulation: | Liquid.InPBS,pH7.2,containing50%glyceroland0.09%sodiumazide. |
| Handling: | Avoidfreeze/thawcycles. |
| Shipping: | ShippedonBlueIce |
| LongTermStorage: | -20°C |
| ScientificBackground: | SynapticvesiclefusionreactionsaremediatedbyavarietyofSNAPproteins,includingalphaandbetaSNAPsandSNAP-25.TogetherwithsynaptotagminandNSF,alpha-SNAPmodulatestheinteractionofSNAP25,VAMP,andsyntaxininanATP-dependentmannertoforma20Scomplexassociatedwithsynapticvesicledockingandfusion.beta-SNAPinteractswithsynaptotagminandmaybeinvolvedincalcium-regulatedexocytosis. |