| AlternativeName: | Sirtuin-3 |
| Host: | Rabbit |
| Immunogen: | RecombinanthumanSIRT3. |
| UniProtID: | Q9NTG7 |
| Speciesreactivity: | Human,Rat Bovine |
| Applications: | IHC(PS),WB |
| RecommendedDilutions/Conditions: | WesternBlot(1:1,000) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| Formulation: | Liquid.InPBS. |
| Handling: | Avoidfreeze/thawcycles.Afteropening,preparealiquotsandstoreat-20°C. |
| Shipping: | ShippedonDryIce |
| LongTermStorage: | -20°C |
| ScientificBackground: | SIRT3issynthesizedasaninactiveprecursorproteinwhosemature,activeformislocatedinthemitochondrialmatrixand/orontheinnermitochondrialmembrane.ResearchshowingthatcaloricrestrictionelevatesSIRT3expressioninmouseadiposetissueandtheabsenceofaSIRT3allelelackinganenhancerelementinlong-livedmensuggestapossibleconnectionbetweenSIRT3expressionandlongevity. |