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| AlternativeName: | ETB-receptor |
| Host: | Sheep |
| Immunogen: | Syntheticpeptidecorrespondingtoaa424-437(K424ANDHGYDN FRSSNN437)ofC-terminalratETB-receptor(endothelinBreceptor). |
| UniProtID: | P21451 |
| Speciesreactivity: | Human,Mouse,Rat Sheep |
| Specificity: | RecognizesthecytoplasmicsideoftheETB-receptor.DetectsisoformsAandCinhuman. |
| Applications: | IHC(FS),WB |
| RecommendedDilutions/Conditions: | Immunohistochemistry(paraffinsections,2.5µg/ml) Immunohistochemistry(frozensections,10µg/ml) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| ApplicationNotes: | ThispAbwasgeneratedagainstthecytoplasmicportionofETB-receptor,permeabilizationisrequiredforimmunochemicalanalysis. Detectsbandsof34-52kDabyWesternblot. Doesnotblockthebindingofendothelinstothereceptor. |
| PurityDetail: | Epitope-affinitypurifiedandsterilefiltered. |
| Formulation: | Liquid.InTRIS-citrate-phosphatebuffer,pH7-8,containing0.1%sodiumazide. |
| Shipping: | ShippedonBlueIce |
| ShortTermStorage: | +4°C |
| LongTermStorage: | -20°C |
| ScientificBackground: | Endothelinsareafamilyofpeptidesthatarepotentvasoconstrictorsproducedbymammalianvascularendothelialcells.Thereceptorsfortheendothelinsarefoundonvarioustissuesincluding,butnotrestrictedto,lungandintestine. |