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| AlternativeName: | SerpinH1,Colligin,Gp46,Heatshockprotein47,Collagen-bindingprotein |
| Clone: | M16.10A1 |
| Host: | Mouse |
| Isotype: | IgG2bλ |
| Immunogen: | NativeratHSP47. |
| UniProtID: | P50454 |
| GenBankID: | X61598 |
| Speciesreactivity: | Human,Mouse,Rat Bovine,Chicken,Dog,Guineapig,Hamster,Monkey,Porcine,Rabbit,Sheep |
| Applications: | IHC,WB |
| RecommendedDilutions/Conditions: | Immunohistochemistry(1:50) WesternBlot(1:1,000,ECL) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication. |
| ApplicationNotes: | Detectsabandof~47kDabyWesternblot. |
| PurityDetail: | ProteinGaffinitypurified. |
| Formulation: | Liquid.InPBS,pH7.2,containing50%glyceroland0.09%sodiumazide. |
| Handling: | Avoidfreeze/thawcycles. |
| Shipping: | ShippedonBlueIce |
| LongTermStorage: | -20°C |
| ScientificBackground: | Hsp47,alsoknownascolliginandgp46,isanER-residentcollagen-specificstressglycoproteininvolvedinthesynthesisandassemblyofvaroiuscollagensasamolecularchaperone.Hsp47isamemberoftheserpinsuperfamily,butlocalizestotheERviabindingofitsC-terminalRDELsequencetoKDELreceptorsintheER.Hsp47bindsprocollagenco-translationallyasitenterstheER,anddissociatespriortoitssecretion. |