企业QQ
官方微信
| AlternativeName: | fibrinprecursor |
| Clone: | 1D6 |
| Host: | Mouse |
| Isotype: | IgG1κ |
| Immunogen: | Humanfibrinogenfromplasma. |
| UniProtID: | P02671(αchain),P02675(βchain),P02679(γchain) |
| Speciesreactivity: | Human |
| Applications: | ELISA,WB |
| ApplicationNotes: | Detectsabandof~340kDabyWesternblot. |
| PurityDetail: | ProteinA/G-affinitypurified. |
| Formulation: | Liquid.In0.01Mphosphatebuffer,pH7.4,containing0.5Msodiumchlorideand15mMsodiumazide. |
| Shipping: | BlueIceNotFrozen |
| ShortTermStorage: | +4°C |
| ScientificBackground: | Fibrinogen,theprecursoroffibrin,isthecoagulableproteininthebloodplasmaofvertebrates.Fibrinogenconsistsasadimerof3pairsofnon-identicalchains,aa(Mr=66,800),Bb(Mr=52,000)andg(Mr=46,500),cross-linkedbydisulfidebondsintheirN-terminalsegments.Themoleculehas2-terminalDdomainsandonecentralEdomain,withallthreedomainsseparatedwhenfibrinogenisdegradatedbyplasmin.Themolecularweightis340kDa.Concentrationinhumanplasmais2-3mg/mL. |