Deprecated: Required parameter $cat_id follows optional parameter $type in /www/wwwroot/ebimall.com/systems/hong.php on line 2088

Deprecated: Required parameter $where follows optional parameter $tree_id in /www/wwwroot/ebimall.com/systems/hlb.php on line 3505
Tocris/A 331440 dihydrochloride/4697/50/50 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
您好,欢迎您进入188进口试剂采购网网站! 服务热线:4000-520-616
蚂蚁淘商城 | 现货促销 | 科研狗 | 生物在线

Tocris/A 331440 dihydrochloride/4697/50/50 mg
Description:SelectiveH3antagonist
ChemicalName:4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitriledihydrochloride
Purity:≥98%(HPLC)
BiologicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityhistamineH3receptorantagonist(Kivaluesare21.7and22.7nMforratandhumanH3receptors,respectively).ExhibitsselectivityforhumanH3overH1,H2andH4receptors(Kivaluesare2940,14400and>10000nMrespectively).Showntoreduceweightinadiet-inducedobesitymodel.

TechnicalData

M.Wt422.39
FormulaC22H27N3O.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1049740-32-0
PubChemID16078942
InChIKeyXFPYVTSGYYMTFS-GHVWMZMZSA-N
SmilesCN(C)[C@H](CC3)CN3CCCOC1=CC=C(C2=CC=C(C#N)C=C2)C=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO8.4520
water42.24100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight422.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.37mL11.84mL23.67mL
5mM0.47mL2.37mL4.73mL
10mM0.24mL1.18mL2.37mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
新闻动态
行业前沿
技术文章
最新产品