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Subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. Increases channel opening efficiency and enhances NMDA receptor responses.
CIQ is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
| M. Wt | 467.94 |
| Formula | C26H26ClNO5 |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 486427-17-2 |
| PubChem ID | 4231127 |
| InChI Key | VYMILMYEENZHAR-UHFFFAOYSA-N |
| Smiles | O=C(C3=CC(Cl)=CC=C3)N2C(COC4=CC=C(OC)C=C4)C1=CC(OC)=C(OC)C=C1CC2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 46.79 | 100 | |
| ethanol | 4.68 | 10mM with sonication |
The following data is based on the product molecular weight 467.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.14 mL | 10.69 mL | 21.37 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.27 mL |
| 10 mM | 0.21 mL | 1.07 mL | 2.14 mL |
| 50 mM | 0.04 mL | 0.21 mL | 0.43 mL |
References are publications that support the products' biological activity.
Mullasseril et al (2010) A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. Nat.Commun. 1 1 PMID: 20975674
Keywords: CIQ, supplier, NMDA, receptors, potentiators, NR2C, NR2D, subunits, enhances, opening, efficiency, NMDA, Receptors, NMDA, Receptors, Tocris Bioscience
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