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Mixednon-peptideneuropeptideYY1(NPYY1)andneuropeptideFF(NPFF)receptorantagonist(Kivaluesare1.1,79,108,>1000,>1000and>1000forrNPYY1,hNPFF2,rNPFF,rNPYY2,rNPYY4andrNPYY5respectively).Producesananxiogenic-likeeffectinratsfollowingi.c.v.administration.
| M.Wt | 701.61 |
| Formula | C27H31N5O3.2CF3CO2H |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| PubChemID | 121513845 |
| InChIKey | FSBMUMHPXBMVJF-MQWQBNKOSA-N |
| Smiles | OC1=CC=C(CNC([C@H](NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)CCCNC(N)=N)=O)C=C1.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 70.16 | 100 | |
| water | 7.02 | 10mMwithsonication |
Thefollowingdataisbasedontheproductmolecularweight701.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.43mL | 7.13mL | 14.25mL |
| 5mM | 0.29mL | 1.43mL | 2.85mL |
| 10mM | 0.14mL | 0.71mL | 1.43mL |
| 50mM | 0.03mL | 0.14mL | 0.29mL |
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