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Potent and selective CECR2 (cat eye syndrome chromosome region, candidate 2) inhibitor (IC50 = 47 nM). Selective for CECR2 over a panel of bromodomains.
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the NVS-CECR2-1 probe summary on the SGC website.
| M. Wt | 495.68 |
| Formula | C27H37N5O2S |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1992047-61-6 |
| PubChem ID | 117072550 |
| InChI Key | XVECNLUKQDKOST-UHFFFAOYSA-N |
| Smiles | CC(C1)(C)NC(C)(C)CC1N2C=CC3=C2C=CC(C4=NC(S(=O)(CCC)=O)=NC(NC5CC5)=C4)=C3 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 49.57 | 100 |
The following data is based on the product molecular weight 495.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.02 mL | 10.09 mL | 20.17 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.03 mL |
| 10 mM | 0.2 mL | 1.01 mL | 2.02 mL |
| 50 mM | 0.04 mL | 0.2 mL | 0.4 mL |
References are publications that support the products' biological activity.
Keywords: NVS-CECR2-1, supplier, Potent, selective, CECR2, cat, eye, syndrome, chromosome, region, candidate, 2, inhibitors, inhibits, bromodomains, Bromodomains, Bromodomains, Tocris Bioscience
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