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Tocris/Sinomenine hydrochloride/3848/50/50 mg
Description:Anti-inflammatory;causesmastcelldegranulationandhistaminerelease
ChemicalName:9α,13α,14α-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-onehydrochloride
Purity:≥98%(HPLC)
BiologicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Naturalanti-inflammatorymorphinananalog.Causesdegranulationofmastcellsinmammaliantissuestoreleasehistamineandsuppressesproductionofproinflammatorycytokines.Alsodisplaysantinociceptiveactivity,possiblythroughactivationoftheμ-opioidreceptor.Stimulatesshort-termrenewalofhumanembryonicstemcells(ESCs)invitro.

TechnicalData

M.Wt365.85
FormulaC19H23NO4.HCl
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber6080-33-7
PubChemID90488887
InChIKeyYMEVIMJAUHZFMW-QKCNXVMZSA-N
SmilesCN4C2[C@]3([H])[C@@](CC(C(OC)=C3)=O)(CC4)C1=C(O)C(OC)=CC=C1C2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water36.59100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight365.85.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.73mL13.67mL27.33mL
5mM0.55mL2.73mL5.47mL
10mM0.27mL1.37mL2.73mL
50mM0.05mL0.27mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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