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Tocris/SR 2640 hydrochloride/1804/50/50 mg

Description:Potent,selectiveLTD4/LTE4receptorantagonist
ChemicalName:2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoicacidhydrochloride
Purity:≥99%(HPLC)
BiologicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivecompetitiveleukotrieneD4andE4receptorantagonist.InhibitsLTD4-butnothistamine-inducedguineapigileumandtracheacontraction(pA2=8.7).AlsoinhibitsLTD4-attenuationofhumanPMNchemotaxis.Orallyactiveinvivo.

CompoundLibraries

SR2640hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt406.87
FormulaC23H18N2O3.HCl
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber146662-42-2
PubChemID45073453
InChIKeyKDSYWFCTUKABKE-UHFFFAOYSA-N
SmilesCl.OC(=O)C1=CC=CC=C1NC1=CC(OCC2=CC=C3C=CC=CC3=N2)=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO20.3450

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight406.87.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.46mL12.29mL24.58mL
5mM0.49mL2.46mL4.92mL
10mM0.25mL1.23mL2.46mL
50mM0.05mL0.25mL0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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