企业QQ
官方微信
Potent,positiveallostericmodulator/allostericagonistatmGlu4receptors(EC50=798and693nMathumanandratmGlu4receptorsrespectively).ActiveininvivomodelsofParkinson'sdiseasefollowingi.c.v.administration.SodiumsaltofVU0155041(Cat.No.3248).
| M.Wt | 338.16 |
| Formula | C14H14Cl2NNaO3 |
| Storage | DesiccateatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 1259372-69-4 |
| PubChemID | 90488828 |
| InChIKey | ISTRFEKLZQLUBR-ZQMRVLLOSA-L |
| Smiles | [Na+].[Na+].[O-]C(=O)[C@H]1CCCC[C@H]1C(=O)NC1=CC(Cl)=CC(Cl)=C1.[O-]C(=O)[C@@H]1CCCC[C@@H]1C(=O)NC1=CC(Cl)=CC(Cl)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 8.45 | 25 |
Thefollowingdataisbasedontheproductmolecularweight338.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.96mL | 14.79mL | 29.57mL |
| 5mM | 0.59mL | 2.96mL | 5.91mL |
| 10mM | 0.3mL | 1.48mL | 2.96mL |
| 50mM | 0.06mL | 0.3mL | 0.59mL |