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Tocris/8MPDOT/1035/50/50 mg

Description:Melatoninagonist
ChemicalName:8-Methoxy-2-propionamidotetralin
Purity:≥99%(HPLC)
BiologicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Melatoninreceptoragonist,20-foldselectivefortheMT2(vsMT1)subtype.AthumanrecombinantMT1andMT2receptors,displayspKivaluesof8.23and8.95respectively.

CompoundLibraries

8-M-PDOTisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt233.31
FormulaC14H19NO2
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber134865-70-6
PubChemID5170952
InChIKeyRVIGBTUDFAGRTQ-UHFFFAOYSA-N
SmilesCCC(=O)NC1CCC2=C(C1)C(OC)=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto50mMinethanolandto100mMinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight233.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.29mL21.43mL42.86mL
5mM0.86mL4.29mL8.57mL
10mM0.43mL2.14mL4.29mL
50mM0.09mL0.43mL0.86mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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