企业QQ
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HighaffinityH3receptorantagonist(Ki=43.8nM).DisplaysselectivityagainstH1andH2receptors(IC50>10μM).Increasesthereleaseofhistamineinthecerebralcortex.Displaysnoactivityathistaminemethyltransferaseinvitroatconcentrationsupto3μM.Brainpenetrant.
| M.Wt | 317.47 |
| Formula | C19H31N3O |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 152241-24-2 |
| PubChemID | 9839975 |
| InChIKey | YTCGNPGLMAECND-UHFFFAOYSA-N |
| Smiles | O=C(CCCCC3CCCCC3)N(CC2)CCC2C1=CN=CN1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.75 | 100 | |
| ethanol | 31.75 | 100 |
Thefollowingdataisbasedontheproductmolecularweight317.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.15mL | 15.75mL | 31.5mL |
| 5mM | 0.63mL | 3.15mL | 6.3mL |
| 10mM | 0.31mL | 1.57mL | 3.15mL |
| 50mM | 0.06mL | 0.31mL | 0.63mL |