SelectiveERRinverseagonist(IC50=~400nM).DisplaysnoantagonistactivityatERRorERatconcentrationsbelow10M.InterfereswithPPARcoactivator-1(PGC-1)/ERR-dependentsignaling:inhibitsPGC-1inductionofERRandMAO-BgeneexpressionanddownregulatestheconstitutivetranscriptionalactivityofERRinnumerouscelllines.
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocrisproductsareintendedforlaboratoryresearchuseonly,unlessstatedotherwise.
*Whenpreparingstocksolutionsalwaysusethebatch-specificmolecularweightoftheproductfoundontheviallabelandSDS/CoA(availableonline).
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
关键词:XCT790,XCT790supplier,XCT790,ERRalpha,ERRa,ERR,antagonists,inverse,agonists,PPAR,PPARg,PPARgamma,coactivator-1,coactivator-1alpha,coactivator-1a,PGC-1,PGC-1alpha,PGC-1a,signaling,signalling,Estrogen,and,Related,Receptors,3928,TocrisBioscience
$50/€35/£30/$50CAN/¥300Yuan/¥5000Yenforfirsttoreviewwithanimage
$25/€18/£15/$25CAN/¥75Yuan/¥1250Yenforareviewwithanimage
$10/€7/£6/$10CAD/¥70Yuan/¥1110Yenforareviewwithoutanimage
Tocris提供以下领域的科研文献,以展现我们的产品。您不妨现在就索取*或下载所需的文献!
*请注意,Tocris仅会向正规科研企业/机构地址发送文献。
Bio-Techneappreciatesthecriticalrolethatyouandourproductsandservicesplayinresearcheffortstofurtherscientificinnovationanddiscovery.WearecontinuallyassessingourmanufacturingandsuppliercapabilitiesduringtheCOVID-19situationandareimplementingprecautionarymeasurestoensureuninterruptedsupplyofproductsandservices.Currently,andasweabidebylocalshelterinplaceordersacrosstheworld,wearefullyoperationalanddonotanticipateanymaterialsupplydisruptionsacrossourBio-Technebrandsandproductlines.Asthesituationevolves,ourgoalistoutilizepreventivemeasurestoreducethethreatthatCOVID-19posestoourabilitytomeettheneedsofourcustomersglobally.
Bio-Techne
WHERESCIENCEINTERSECTSINNOVATIONTM