Innova Biosciences/ATP Agarose/5200002A/Control Resin 2ml

Affinity resins have been widely used for the purification of enzymes and other proteins that bind nucleotides and related molecules. ATP-agarose resin comprises ATP attached to agarose beads via its gamma-phosphate. A long hydrophilic spacer (14-atom) is used to minimize unwanted hydrophobic interactions and to facilitate unhindered interactions with biomolecules. The ligand is coupled through the gamma-phosphate group which means that the resin is resistant to phosphatases found in many crude tissue extracts.

Benefits include

Quick and easy-to-use
Extremely stable
Can be used in column chromatography or batch processing
Stringently QC tested

Please get in contact with us to know more about this product.

ARD1-mediated aurora kinase A acetylation promotes cell proliferation and migration - Oncotarget. (2017)

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Innova Biosciences/ATP Agarose/5200002A/Control Resin 2ml

Benefits include

ARD1-mediated aurora kinase A acetylation promotes cell proliferation and migration - Oncotarget. (2017)

ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation - Nature Commun. (2016)

Deguelin analog SH-1242 inhibits Hsp90 activity and exerts potent anticancer efficacy with limited neurotoxicity - Cancer Res. (2015)

The Kinase Homology Domain of Receptor Guanylyl Cyclase C:? ATP Binding and Identification of an Adenine Nucleotide Sensitive Site - Biochemistry (2006)

Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose- The Plant Journal (2006)

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling - PNAS (2007)

HDAC6 inhibition enhances 17-AAG–mediated abrogation of hsp90 chaperone function in human leukemia cells - Blood (2008)

Role of Acetylation and Extracellular Location of Heat Shock Protein 90? in Tumor Cell Invasion- Cancer Research (2008)

(?)-Epigallocatechin-3-gallate Is a Novel Hsp90 Inhibitor- Biochemistry (2009)

Regulation of Calcium/Calmodulin-dependent Kinase IV by O-GlcNAc Modification - J Biol Chem (2009)

Compositions and Methods for Inhibiting Cancer Metastasis - US Patent Application 20100111943

Evolution of functional nucleic acids in the presence of nonheritable backbone heterogeneity- PNAS (2011)

A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence - JBC (2011)

Functional Characterization of Naturally Occurring Transglutaminase 2 Mutants Implicated in Early-Onset Type 2 Diabetes- Journal of Molecular Endocrinology (2012)

Thr90 phosphorylation of Hsp90? by protein kinase A regulates its chaperone machinery - Biochem. J. (2012)

Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state- Scientific Reports (2014)

A structure-specific nucleic acid-binding domainconserved among DNA repair proteins - PNAS (2014)

Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-Terminal Domain of Heat Shock Protein 90 - Molecular Pharmacology (2015)

The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis - PLoS One (2015)