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LifeSensors/UB305-25µg MuRF2/UB-0305-0025

Specifications

MuRF2 is a RING domain E3 ligase that is involved in the conjugation of ubiquitin to target substrates. MuRF2 has been demonstrated to function with the E2 enzyme UBE2D3 (UbcH5c) in vitro. MuRF2 is also known as TRIM55 (tripartite motif containing 55) containing a RING-finger/B-box/coiled-coil tripartite fold. MuRF2 has been implicated along with MuRF1 as regulators of protein degradation in striated muscle.

Info

Purity>90% by SDS-PAGE
Molecular Weight60.5 kDa (without SUMO tag)
Quantity25 μg
Physical StateLiquid
BufferBuffered Saline with 10% glycerol
SourceHuman recombinant expressed in bacteria
TagSUMO
ActivityTypical enzyme concentration of 20-1000nM is used for in vitro conjugation depending on assay conditions.
Storage-80°C. Avoid repeated freeze/thaw cycles
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