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LifeSensors/SI215-1mg Ubiquitin-K29R/SI215-1mg Ubiquitin-K29R

Recombinantubiquitinhavingasinglesubstitutionofarginineforlysineatposition29.

UbiquitinisasmallpolypeptidethatcanbeconjugatedviaitsC-terminustoaminegroupsoflysineresidueontargetproteins.Thisconjunctionisreferredtoasmonoubiquitylation.Additionalubiquitinmoietiescanbesubsequentlyconjugatedtothisinitialubiquitin,utilizinganyone(ofseven)lysineresiduesonthesurfaceofubiquitin.Theformationoftheseubiquitinchainsisreferredtoaspolyubiquitylation.



Info


SourceHumanrecombinant
Formliquid
Molecularweight8,592Da
Purity>=95%byRP-HPLC
AffinityTagNone
Concentration4mg/mL
Buffer20mMTris,pH7.5,0.15MNaCl,10%glycerol
StorageLongtermstorageat-80°C.Avoidmultiplefreeze/thawcycles.
StABIlity1yearunderrecommendedstorageconditions


Applications

  • InvestigationofE1-E2-E3mediatedubiquitinligation.
  • InvestigationofDUBlinkagespecificity.

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