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Prospec/PKIB Human/Protein Kinase Inhibitor Beta Human Recombinant/1mg/PKA-003-1mg-1mg

Cataloguenumber

PKA-003

Synonyms

cAMP-dependentproteinkinaseinhibitorbeta,PKI-beta,PKIB,PRKACN2,FLJ23817.

Introduction

cAMP-dependentproteinkinaseinhibitorbeta(PKIB)belongstothecAMP-dependentproteinkinaseinhibitorfamily.PKIBmayinteractwiththecatalyticsubunitofcAMP-dependentproteinkinaseandfunctionasacompetitiveinhibitor.

Description

PKIBHumanRecombinantproducedinE.Coliisasingle,non-glycosylated,polypeptidechaincontaining98aminoacids(1-78)andhavingamolecularmassof10.6kDa(MolecularsizeonSDS-PAGEwillappearhigher).PKIBisfusedtoa20aaHis-TagatN-terminusandpurifiedbyproprietarychromatographictechniques.

Source

EscherichiaColi.

PhysicalAppearance

Sterilefilteredcolorlesssolution.

Formulation

PKIBsolution(1mg/ml)20mMTris-HClbuffer(pH8.0),20%glycerol,0.1MNaCland1mMDTT.

StABIlity

Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.

Purity

Greaterthan95.0%asdeterminedbySDS-PAGE.

Aminoacidsequence

MGSSHHHHHHSSGLVPRGSHMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK.

SafetyDataSheet

SDS

Usage

Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
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