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Prospec/GDI1 Human/GDP Dissociation Inhibitor 1 Human Recombinant/10µg/PRO-2023-10µg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Prospec/GDI1 Human/GDP Dissociation Inhibitor 1 Human Recombinant/10µg/PRO-2023-10µg

Cataloguenumber

PRO-2023

Synonyms

RabGDPdissociationinhibitoralpha,RabGDIalpha,GDPDissociationInhibitor1,GDI1,Guanosinediphosphatedissociationinhibitor1,GDI-1,Oligophrenin-2,XAP-4,GDIL,OPHN2,RABGDIA,XAP4,MRX41,MRX48,1A,RABGD1A.

Introduction

GDPDissociationInhibitor1(GDI1)isexpressedmainlyinneuralandsensorytissues.GDI1regulatestheGDP/GTPexchangereactionofnearlyallRabproteinsbyinhibitingthedissociationofGDPfromthem,andthesubsequentbindingofGTPtothem.GDI1isalsopromotingthedissociationofGDP-boundRabproteinsfromthemembraneandinhibitstheiractivation.MutationsinGDI1havebeenassociatedwithX-linkednonspecificmentalretardation.

Description

GDI1HumanRecombinantproducedinE.coliisasinglepolypeptidechaincontaining470aminoacids(1-447)andhavingamolecularmassof53kDa.GDI1isfusedto23aminoacidHis-tagatN-terminus&purifiedbyproprietarychromatographictechniques.

Source

EscherichiaColi.

PhysicalAppearance

SterileFilteredclearsolution.

Formulation

TheGDI1solution(0.25mg/1ml)contains20mMTris-HClbuffer(pH8.0),0.15MNaCl,20%glyceroland1mMDTT.

StABIlity

Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Avoidmultiplefreeze-thawcycles.

Purity

Greaterthan90.0%asdeterminedbySDS-PAGE.

Aminoacidsequence

MGSSHHHHHHSSGLVPRGSHMGSMDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKDIYKRMAGTAFDFENMKRKQNDVFGEAEQ.

SafetyDataSheet

SDS

Usage

Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theymaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.
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