| Isotype | IgG |
| ProductType | PolyclonalAntibody |
| Units | 100µg |
| Host | Rabbit |
| Speciesreactivity | Human |
| Application | WesternBlotting |
BackgroundAPM2isan~8kDaproteinwhichuntilrecentlywasfoundonlyintheESTdatabasebutneverasanexpressedprotein.APM2hassincebeenshowntobeassociatedwithcisplatinresistanceincelllines.APM2isnotfoundincisplatinsensitivecelllines.ThesedataimplicateAPM2inthedevelopmentofcisplatinresistanceintumorcells.
Synonyms:ADIposemostabundantgenetranscript2protein,apM-2,APM2,C10orf116
Source
Immunogen:SyntheticpeptidederivedfromhumanAPM2protein
Product
ProductForm:Unconjugated
Formulation:Providedassolutioninphosphatebufferedsalinewith0.08%sodiumazide
PurificationMethod:AmmoniumSulfatePrecipitation
Concentration:Seevialforconcentration
ApplicationsAntibodycanbeusedforWesternblotting(1-5µg/mlstartingdilution).Optimalconcentrationshouldbeevaluatedbyserialdilutions.
FunctionalAnalysis:WesternBlotting
PositiveControl:Adiposetissue,corneaandliver.
StorageProductshouldbestoredat-20ºC.Aliquottoavoidfreeze/thawcycles
ProductStABIlity:Productsarestableforoneyearfrompurchasewhenstoredproperly
ShippingConditions:Shipatambienttemperature,freezeuponarrival
CautionThisproductisintendedFORRESEARCHUSEONLY,andFORTESTSINVITRO,notforuseindiagnosticortherapeuticproceduresinvolvinghumansoranimals.Itmaycontainhazardousingredients. PleaserefertotheSafetyDataSheets(SDS)foradditionalinformationandproperhandlingprocedures.Disposeproductremaindersaccordingtolocalregulations.Thisdatasheetisasaccurateasreasonablyachievable,butNordic-Mubioacceptsnoliabilityforanyinaccuraciesoromissionsinthisinformation.
References1.Scott,B.J.,etal.APM2isanovelmediatorofcisplatinresistanceinavarietyofcancercelltypesregardlessofp53orMMRstatus.Int.J.Cancer2009,125,1193-1204
ProteinReference(s)
DatabaseName:UniProt
Accessionnumber:Q15847
SpeciesAccession:Human
SafetyDatasheet(s)forthisproduct:NM_SodiumAzide/wp-content/uploads/SDS/AntibodySDSwithSodiumAzideNoridic-MUbio.pdf
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