GenWay/hTRPC3HEK293 Recombinant Cell line/GWBPS9311/1x10(6)cells

Description:

Description:RecombinantHEK293celllineexpressinghumanTRPC3(transientreceptorpotentialcationchannel,subfamilyC,member3,accessionnumberNM_003305).FormatEachvialcontains1X10^6cellsin1mlof10%DMSO.IntroductionTRPC3channelbelongstothetransientreceptorpotentialchannel(TRP)superfamilywhichisdividedintosevenmainsubfamilies.TRPchannelsshareasimilararchitectureofsix-transmembranedomainsandfunctionastetramers.Mostchannelsarepermeabletocalciumandmonovalentcations(Vassortetal,2009).Specifically,TRPC3channelbelongstoacanonicalTRP(TRPC)subfamilythatisinvolvedincalciumentry.TRPC3isactivatedthroughphospholipaseC-linkedreceptors.WhenexpressedinHEK293cells,TRPC3behavesasareceptoractivatedchannelwithconstitutiveactivitythatcannotbefurtherincreasedbystoredepletion(Trebaketal,2002).

Host:HEK293(human)

GINum:NM_003305

Format:aqueoussolutioncontainingDMSO

ScientificCategory:IonChannel

Species:human

AdditionalInformation:

Name	hTRPC3-HEK293RecombinantCellline
RelatedProductNames	hTRPC3-HEK293RecombinantCellline
Source	HEK293(human)
GINumber	NM_003305
Format	AqueousSolutionContainingDmso
Reactivity	Human
Storage	liquidN2
IntendedUse	ResearchUseOnly