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GenWay/Free Thyroxine (FT4) ELISA/GWBBQK154/96 Well Plate188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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GenWay/Free Thyroxine (FT4) ELISA/GWBBQK154/96 Well Plate

Description:

DescriptionThefT4ELISAkitisusedforthequantitativemeasurementoffreeThyroxine(fT4)inhumanserumorplasma.Over99%ofthyroxine(T4)circulatesinbloodisboundtocarrierproteins;thyroxine-bindingglobulin(TBG).However,onlythefree(unbound)portionofThyroxineisresponsibleforthebiologicalaction.Further,theconcentrationsofthecarrierproteinsarealteredinmanyclinicalconditions,suchaspregnancy.Innormalthyroidfunctionastheconcentrationsofthecarrierproteinsalters,thetotalT4levelchangessothatthefreeT4concentrationremainsconstant.Thus,measurementsoffreeT4concentrationscorrelatemorereliablywithclinicalstatusthantotalT4levels.TheincreaseintotalT4levelsassociatedwithpregnancy,oralcontraceptivesandestrogentherapyresultinhighertotalT4levelswhilethefreeT4concentrationremainsbasicallyunchanged.
SpeciesHuman
SampleTypeSerumorPlasma

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NameFreeThyroxine(FT4)ELISA
ShortDescriptionThefT4ELISAkitisusedforthequantitativemeasurementoffreeThyroxine(fT4)inhumanserumorplasma.Over99%ofthyroxine(T4)circulatesinbloodisboundtocarrierproteins;thyroxine-bindingglobulin(TBG).However,onlythefree(unbound)portionofThyroxineisresponsibleforthebiologicalaction.Further,theconcentrationsofthecarrierproteinsarealteredinmanyclinicalconditions,suchaspregnancy.Innormalthyroidfunctionastheconcentrationsofthecarrierproteinsalters,thetotalT4levelchangessothatthefreeT4concentrationremainsconstant.Thus,measurementsoffreeT4concentrationscorrelatemorereliablywithclinicalstatusthantotalT4levels.TheincreaseintotalT4levelsassociatedwithpregnancy,oralcontraceptivesandestrogentherapyresultinhighertotalT4levelswhilethefreeT4concentrationremainsbasicallyunchanged.
ReactivityHuman