GenWay/Human BMP2 ELISA Kit/GWBZZD138/1x96 well plate

Description:

Bonemorphogeneticprotein-2(BMP-2,BMP2A)belongstothetransforminggrowthfactorbeta(TGF-beta)superfamily.Itisthoughttobeinvolvedincartilageandboneformationduringembryogenesis,butmayhaveadditionalfunctionsinmorphogenesisasimpliedbyitsexpressioninvariousorgansandembryonictissuesofmice.1BMP-2hasbeenidentifiedasacandidatemediatorofretinoidactivity.BMP-2proteininducesmedulloblastomacellapoptosis,whereastheBMP-2antagonistnogginblocksbothretinoidandBMP-2-inducedapoptosis.BMP-2alsoinducesp38mitogen-activatedproteinkinase(MAPK),whichisnecessaryforBMP-2andretinoid-inducedapoptosis.2Bonemorphogenicproteins(BMPs)areknowntopromoteosteogenesis,andclinicaltrialsarecurrentlyunderwaytoevaluatetheabilityofcertainBMPstopromotefracture-healingandspinalfusion.3ThestandardproductusedinthiskitisrecombinanthumanBMP-2,constitutingdimerbytwochainsof114aminoacidswiththemolecularmassof26KDa.

AdditionalInformation:

Name	HumanBMP-2ELISAKit
RelatedProductNames	BDA2|BMP-2|BMP-2A|Bmp2|BMP2_HUMAN|BMP2A|Bonemorphogeneticprotein2|Bonemorphogeneticprotein2A
ShortDescription	SandwichELISAkitofQuantitativeDetectionforHumanBMP-2
Immunogen	CHO,Q283-R396
StandardRange	62.5pg/ml-4000pg/ml.Testhasasensitivityof<2="">
SampleType	ThiskitisusedforquantitativedetectionofhumanBMP-2inbonetissue,cellculturesupernatesandserum.
Specimen/Volumes	RefertoManual
SwissProtNumber	C8C060
Concentration	LotSpecific
Applications	ELISA
GINumber	650
Stability	Fourmonthsat4Candeightmonthsat-20C.
Reactivity	ReactivetoHuman.Thereisnodetectablecross-reactivitywithotherrelevantproteins.
KitSize	1x96wellplate
Storage	Storeat4°Cfor6months,at-20°Cfor12months.Avoidmultiplefreeze-thawcycles(Shippedwithwetice.)
IntendedUse	ResearchUseOnly