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ubpbio/UCHL1/H1100/25 µg

Deubiquitinatingenzymes(DUBs)areproteasesthatpossestheabilitytocleaveubiquitinchainsortheisopeptidebondthatconjugatesubiquitinwithasubstrate.Humancellshaveapproximately100DUBsthatplayimportantrolesinregulatingvariouscellularevents.UCHL1isoneofthefourmembersoftheubiquitinC-terminalhydrolase(UCH)family.Itisthoughttobemainlyinvolvedincleavingproubiquitinproteinsintomonomericubiquitin.

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Deubiquitinatingenzymes(DUBs)areproteasesthatpossestheabilitytocleaveubiquitinchainsortheisopeptidebondthatconjugatesubiquitinwithasubstrate.Humancellshaveapproximately100DUBsthatplayimportantrolesinregulatingvariouscellularevents.UCHL1isoneofthefourmembersoftheubiquitinC-terminalhydrolase(UCH)family.Itisthoughttobemainlyinvolvedincleavingproubiquitinproteinsintomonomericubiquitin.

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ProductName:UCHL1
AlsoKnownAs:PARK5;PGP95;PGP9.5;Uch-L1;PGP9.5
CatalogNo.:H1100
Size:25µg
MolecularWeight:24.8kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~95%bySDS-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheetMSDS
NCBIRefSeq:NM_004181
Image(s):N/A
ShippingMethod:Dryiceshipping
References:1.PickartCM,etal.(1985)JBiolChem260(13),7903–7910.
2.WilkinsonKD(1997)FASEBJ11(14),1245–1256.3.LarsenCN,etal.(1998)Biochemistry37(10),3358–3368.
4.Reyes-TurcuFE,etal.(2009)AnnuRevBiochem78,363–397.