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ubpbio/6xHisUbe2E1 (UbcH6)/C1800/25 µg

Ube2E1isanE2enzyme,whichispartoftheE1,E2,andE3cascaderesponsibleforubiquitinationofproteinsubstrates.Ube2E1wasfoundtolocateinthenucleus.It,alongwithUbe2D1,isknowntocomplexwiththeE3ligaseRo52toubiquitinateinterferonregulatorytranscriptionfactorsIRF3andIRF8.Ube2E1canalsocomplexwithaUbligasecalledRING105toubiquitinateatumorsuppressorknownastumor–suppressingsubchromosomaltransferablefragmentcDNA(TSSC5).

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Ube2E1isanE2enzyme,whichispartoftheE1,E2,andE3cascaderesponsibleforubiquitinationofproteinsubstrates.Ube2E1wasfoundtolocateinthenucleus.It,alongwithUbe2D1,isknowntocomplexwiththeE3ligaseRo52toubiquitinateinterferonregulatorytranscriptionfactorsIRF3andIRF8.Ube2E1canalsocomplexwithaUbligasecalledRING105toubiquitinateatumorsuppressorknownastumor–suppressingsubchromosomaltransferablefragmentcDNA(TSSC5).
Images:(Clickimagetoenlarge)
ProductName:6xHis-Ube2E1(UbcH6)
AlsoKnownAs:UBCH6
CatalogNo.:C1800
Size:25µg
MolecularWeight:21.4kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~90%bySDS-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheetMSDS
NCBIRefSeq:NM_003341
Image(s):(Clickimagetoenlarge)
Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurified6xHis-Ube2E1(UbcH6)
ShippingMethod:Dryiceshipping
References:1.NuberU,etal.(1996)JBiolChem271(5),2795–2800.
2.YamadaHY,etal.(2006)Oncogene25(9),1330–1339.3.EspinosaA,etal.(2008)ExpCellRes314,3605–3613.
4.EspinosaA,etal.(2009)JExpMed206,1661–1671.
Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurified6xHis-Ube2E1(UbcH6)

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