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ubpbio/6xHisTRAIL/U1100/50 µg
TRAIL(TNF-relatedapoptosis-inducingligand)isacytokinethatisproducedandsecretedbymostnormaltissuecells.TRAILbindstocellsurfacedeathreceptorsDR4andDR5,bywhichitactivatescaspase-8toinduceapoptosisofcancercellsbutnotofnormalcells.Thisproductcontainstheextracellulardomain(aminoacids95-281)offull-lengthhumanTRAILanditiscompetentforbindingofDR4andDR5.ThisproducthasbeentestedforinducingapoptosisofTRAIL-sensitivecancercelllinesatconcentrationsof1-50ng/mL.

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TRAIL(TNF-relatedapoptosis-inducingligand)isacytokinethatisproducedandsecretedbymostnormaltissuecells.TRAILbindstocellsurfacedeathreceptorsDR4andDR5,bywhichitactivatescaspase-8toinduceapoptosisofcancercellsbutnotofnormalcells.Thisproductcontainstheextracellulardomain(aminoacids95-281)offull-lengthhumanTRAILanditiscompetentforbindingofDR4andDR5.ThisproducthasbeentestedforinducingapoptosisofTRAIL-sensitivecancercelllinesatconcentrationsof1-50ng/mL.
Images:(Clickimagetoenlarge)
ProductName:6xHis-TRAIL
AlsoKnownAs:TNFSF10;TL2;APO2L;CD253;Apo-2L
CatalogNo.:U1100
Size:50µg
MolecularWeight:32.5kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~85%bySDS-PAGE
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheet
NCBIRefSeq:NM_003810.3
Image(s):(Clickimagetoenlarge)
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkers
Lane2:5µgpurified6xHis-TRAIL
ShippingMethod:Dryiceshipping
References:N/A
Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurified6xHis-TRAIL

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