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ubpbio/TNFalpha/U1120/50 µg
TNFalpha(Tumornecrosisfactoralpha)isproducedbyimmuneandepithelialcells.Itplaysimportantrolesinregulatinginflammation,apoptosis,andimmuneresponse.ItexertsitsfunctionmainlybybindingoftwocellsurfacereceptorsTNFR1andTNFR2.TreatingcellswithTNFalphaactivatestheNFkappaB,MAPK,anddeathsignalingpathways.TherecombinantTNFalphaproteinconsistsoftheextracellulardomain(aminoacids77-233)offulllengthTNFalpha.Itinducesapoptosisofvariouscancercellsattheconcentrationof10-100ng/mL+1ug/mLcycloheximide(aproteintranslationinhibitor).ItisgeneratedfromGST-TNFalpha(catlog#U1130)byremovaloftheN-terminalGSTtag.

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TNFalpha(Tumornecrosisfactoralpha)isproducedbyimmuneandepithelialcells.Itplaysimportantrolesinregulatinginflammation,apoptosis,andimmuneresponse.ItexertsitsfunctionmainlybybindingoftwocellsurfacereceptorsTNFR1andTNFR2.TreatingcellswithTNFalphaactivatestheNFkappaB,MAPK,anddeathsignalingpathways.TherecombinantTNFalphaproteinconsistsoftheextracellulardomain(aminoacids77-233)offulllengthTNFalpha.Itinducesapoptosisofvariouscancercellsattheconcentrationof10-100ng/mL+1ug/mLcycloheximide(aproteintranslationinhibitor).ItisgeneratedfromGST-TNFalpha(catlog#U1130)byremovaloftheN-terminalGSTtag.
Images:(Clickimagetoenlarge)
ProductName:TNFalpha
AlsoKnownAs:TNF;DIF;TNFA;TNFSF2;TNF-alpha
CatalogNo.:U1120
Size:50µg
MolecularWeight:25.6kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~85%bySDS-PAGE
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheet
NCBIRefSeq:NM_000594.3
Image(s):(Clickimagetoenlarge)
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkers
Lane2:5µgpurifiedTNFalpha
ShippingMethod:Dryiceshipping
References:N/A
Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurifiedTNFalpha

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