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ubpbio/6xHisSumo 2/E3220/500 µg
SUMO(smallUb-relatedmodifier)isaUb-likeprotein.ThreetypesofSUMOaremostcommonlystudied,SUMO1,SUMO2,andSUMO3.SUMO2andSUMO3arealmostidenticalisoformsandthussharemanyfunctions.LikeUb,SUMOcanbeconjugatedtoitstargetproteinsasapolymericchain.However,SUMO1formschainsinefficientlyascomparedtoSUMO2andSUMO3.SUMOisconjugatedtotargetproteinsbytheE1(SAE1/SAE2),E2(Ube2IorUbc9),E3(RanBP2/Nup358,amongstothers).Proteinsumoylationisinvolvedinmanycellularprocessesincludinggenetranscription.

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SUMO(smallUb-relatedmodifier)isaUb-likeprotein.ThreetypesofSUMOaremostcommonlystudied,SUMO1,SUMO2,andSUMO3.SUMO2andSUMO3arealmostidenticalisoformsandthussharemanyfunctions.LikeUb,SUMOcanbeconjugatedtoitstargetproteinsasapolymericchain.However,SUMO1formschainsinefficientlyascomparedtoSUMO2andSUMO3.SUMOisconjugatedtotargetproteinsbytheE1(SAE1/SAE2),E2(Ube2IorUbc9),E3(RanBP2/Nup358,amongstothers).Proteinsumoylationisinvolvedinmanycellularprocessesincludinggenetranscription.

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ProductName:6xHis-Sumo2
AlsoKnownAs:HSMT3;SMT3B;SUMO3;Smt3A;SMT3H2;MGC117191
CatalogNo.:E3220
Size:500µg
MolecularWeight:10.9kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~95%bySDS-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheet，MSDS
NCBIRefSeq:NM_006937
Image(s):N/A
ShippingMethod:Dryiceshipping
References:1.BoddyMN,etal.(1996)Oncogene13,971–982.
2.BayerP,etal.(1998)JMolBiol280,275–286.3.MelchiorF,(2000)AnnuRevCellDevBiol16,591–626.
4.PraefckeGJK,etal.(2012)TrendsBiochemSci37(1),23–31.5.WernerA,etal.(2012)MolCell46(3),287–298.