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ubpbio/GSTS5a/A3300/25 µg

S5aisoneoftheintegralUbreceptorsofthe26Sproteasome.It’sN-terminalvWAdomaininteractswithRpn9andRpn10onthe26Sproteasome.TheC-terminaldomainofS5acontainstwoUb-interactingmotifs(UIMs)thatbindUbandUbchains.S5apreferstobindpolyUbchains;italsobindsproteinscontainingaUb-likedomain.ItmaydirectlyrecognizeubiquitinatedproteinsorcoordinatewithotherUbreceptorstotargetsubstratesforproteasomaldegradation.

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S5aisoneoftheintegralUbreceptorsofthe26Sproteasome.It’sN-terminalvWAdomaininteractswithRpn9andRpn10onthe26Sproteasome.TheC-terminaldomainofS5acontainstwoUb-interactingmotifs(UIMs)thatbindUbandUbchains.S5apreferstobindpolyUbchains;italsobindsproteinscontainingaUb-likedomain.ItmaydirectlyrecognizeubiquitinatedproteinsorcoordinatewithotherUbreceptorstotargetsubstratesforproteasomaldegradation.
Images:(Clickimagetoenlarge)
ProductName:GST-S5a
AlsoKnownAs:PSMD4;AF;ASF;S5A;AF-1;MCB1;Rpn10;pUB-R5
CatalogNo.:A3300
Size:25µg
MolecularWeight:40.7kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~95%bySDS-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheetMSDS
NCBIRefSeq:NM_002810
Image(s):(Clickimagetoenlarge)
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkersLane2:5µgpurifiedGST-S5a
ShippingMethod:Dryiceshipping
References:1.DeverauxQ,etal.(1994)JBiolChem269(10),7059–7061.
2.BealR,etal.(1996)ProcNatlAcadSci93(2),861–866.3.ChenL,etal.(2002)MolCellBiol22(13),4902–4913.
4.WangQ,etal.(2005)JMolBiol348,727–739.
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightmarkersLane2:5µgpurifiedGST-S5a

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