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ubpbio/VX765/F7121/25 mg
VX-765isanorallyabsorbedprodrugofVRT-043198,apotentandselectiveinhibitorofcaspase-1and4.Inculturesofperipheralbloodmononuclearcellsstimulatedwithbacterialproducts,VRT-043198inhibitedthereleaseofInterleukin(IL)-1βandIL-18,buthadnoaffectthesecretionofothercytokinesincludingIL-α,TNFα,IL-6andIL-8

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VX-765isanorallyabsorbedprodrugofVRT-043198,apotentandselectiveinhibitorofcaspase-1and4.Inculturesofperipheralbloodmononuclearcellsstimulatedwithbacterialproducts,VRT-043198inhibitedthereleaseofInterleukin(IL)-1βandIL-18,buthadnoaffectthesecretionofothercytokinesincludingIL-α,TNFα,IL-6andIL-8

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ProductName:VX-765
AlsoKnownAs:N/A
CatalogNo.:F7121
Size:25mg
CAS:273404-37-8
Formula:C24H33ClN4O6

MolecularWeight:509Da
Form:Lyophilizedpowder
QualityAssurance:>98%byHPLCandNMR
Source:Synthetic
Storage:Eligibleforroomtemperatureshipping.Storeat2-8°Cuponreceiving
PDFDataSheet:DownloadPDFdatasheet
Image(s):N/A
ShippingMethod:Roomtemperatureshipping
References:1.WannamakerW,etal.(2007)JPharmacolExpTher2007,321:509-516.
2.DoitshG,etal.(2014)Nature2014,505:509-514.