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ubpbio/Sumo 1/E3100/500 µg
SUMO(smallUb-relatedmodifier)isaUb-likeprotein.ThreetypesofSUMOaremostcommonlystudied,SUMO1,SUMO2,andSUMO3.SUMO2andSUMO3arealmostidenticalisoformsandthussharemanyfunctions.LikeUb,SUMOcanbeconjugatedtoitstargetproteinsasapolymericchain.However,SUMO1formschainsinefficientlyascomparedtoSUMO2andSUMO3.SUMOisconjugatedtotargetproteinsbytheE1(SAE1/SAE2),E2(Ube2IorUbc9),E3(RanBP2/Nup358,amongstothers).Proteinsumoylationisinvolvedinmanycellularprocessesincludinggenetranscription.

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SUMO(smallUb-relatedmodifier)isaUb-likeprotein.ThreetypesofSUMOaremostcommonlystudied,SUMO1,SUMO2,andSUMO3.SUMO2andSUMO3arealmostidenticalisoformsandthussharemanyfunctions.LikeUb,SUMOcanbeconjugatedtoitstargetproteinsasapolymericchain.However,SUMO1formschainsinefficientlyascomparedtoSUMO2andSUMO3.SUMOisconjugatedtotargetproteinsbytheE1(SAE1/SAE2),E2(Ube2IorUbc9),E3(RanBP2/Nup358,amongstothers).Proteinsumoylationisinvolvedinmanycellularprocessesincludinggenetranscription.

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ProductName:Sumo1
AlsoKnownAs:DAP1;GMP1;PIC1;SMT3;UBL1;OFC10;SENP2;SMT3C;SMT3H3
CatalogNo.:E3100
Size:500µg
MolecularWeight:11.6kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~95%bySDS-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheet，MSDS
NCBIRefSeq:NM_003352
Image(s):N/A
ShippingMethod:Dryiceshipping
References:1.BoddyMN,etal.(1996)Oncogene13,971–982.
2.BayerP,etal.(1998)JMolBiol280,275–286.3.MelchiorF,(2000)AnnuRevCellDevBiol16,591–626.
4.PraefckeGJK,etal.(2012)TrendsBiochemSci37(1),23–31.5.WernerA,etal.(2012)MolCell46(3),287–298.