MCL1 Antibody (OAEC04260)

货号：	OAEC04260
抗体英文名：	MCL1Antibody(OAEC04260)
靶点：	MCL1
宿主：	Mouse
适应物种：	Human
克隆性：	否
保存条件：	Storeat4C,forlongtermstorage,storeat-20C.
形态：	PurifiedantibodyinPBScontaining0.03%sodiumazide
亚型：	IgG1
免疫原：	PurifiedrecombinantfragmentofhumanMCL-1expressedinEColi
规格：	100ug/100ul

NCBIGeneId:4170
SwissprotId:Q07820
Mcl-1(Myeloidcellleukemia-1)isBcl-2-relatedandwasidentifiedasanearly-inductiongenethatincreasedinexpressionduringthedifferentiationofhumanmyeloblasticleukemiacellML-1,orexposuretodifferentDNAdamagingagents.ThelevelofMcl-1isdecreasedinperipheralBlymphocytesundergoingapoptosisfollowingtreatmentwithapoptoticstimulisuchasTGF-alpha1andforskolin.ExpressionofMcl-1isabletodelayapoptosisinducedbyover-expressionofc-mycinCHO5AHSmyccells.InhematopoieticFDC-P1cells,Mcl-1interactswithanotherBcl-2-relatedprotein,Bax,andprolongscellviABIlityaftertreatmentwithdifferentapoptoticreagents.Thismonoclonalantibodydetecteda37kdMCL1inBCBL-1celllysate.-Seemoreat:http://www.avivasySBIo.com/sd/tds/html_datasheet.php?sku=OAEC04260

HepG2cells

ConfocalimmunofluorescenceanalysisofHepG2cellsusingMCL1mousemAb(green).Red.ActinfilamentshavebeenlabeledwithDY-554phalloidin.Blue.DRAQ5fluorescentDNAdye.

Humanlymphnodetissues

Immunohistochemicalanalysisofparaffin-embeddedhumanlymphnodetissuesusingMCL1mousemAbwithDABstaining.

Hela(1),BCBL-1(2),Jurkat(3)andHL60(4)celllysate

WesternblotanalysisusingMCL1mousemAbagainstHela(1),BCBL-1(2),Jurkat(3)andHL60(4)celllysate.