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RSPO2 Recombinant Protein (Human) (OPBG00269)188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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RSPO2 Recombinant Protein (Human) (OPBG00269)
货号：OPBG00269
英文名：RSPO2
保存条件：Storeat-20C.Avoidfreeze/thawcycles.
规格：20ug
NCBIGeneId:340419
SwissprotId:Q6UXX9
TheR-Spondin(Rspo)proteinsbelongtotheRspofamilyofWntmodulators.Currently,thefamilyconsistsoffourstructurallyrelatedsecretedligands(Rspo1-4),allcontainingfurin-likeandthrombospondinstructuraldomains.TheRspoproteinscaninteractwiththeFrizzled/LRP6receptorcomplexinamannerthatcausesthestabilizationandresultingaccumulationoftheintracellularsignalingprotein,beta-catenin.Thisactivityeffectivelyactivatesandincreasesthesubsequentnuclearsignalingofbeta-catenin.R-SpondincanalsobindtothepreviouslydiscoveredG-proteincoupledreceptors,LGR-4andLGR-5.Rspo/beta-cateninsignalingcanactasaninducerofthetransformedphenotype,andcanalsoregulatetheproliferationanddifferentiationofcertainstemcellpopulations.
RecombinanthumanR-Spondin-2isa24.4kDaproteinconsistingof212aminoacidresidues.
Duetoglycosylation,R-Spondin-2migratesatanapparentmolecularweightofapproximately30.0kDabySDSPAGEanalysisunderreducingconditions.-Seemoreat:http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OPBG00269

RSPO2 Recombinant Protein (Human) (OPBG00269) using SDS-PAGE

R-Spondin-2SDS-PAGE

RSPO2RecombinantProtein(Human)(OPBG00269)usingSDS-PAGE

温馨提示：不可用于临床治疗。

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