企业QQ
官方微信
Doripenemisaparenterally-admiNISTredantimicrobialofthecarbapenemfamily,withminimuminhibitoryconcentrations(MIC)of0.25ug/mLinPseudomonasaeruginosaandEscherichiacoli.[1]Similartootherb-lactamantibiotics,Doripenemformsstableacyl-enzymeswithpencillin-bindingproteins,leADIngtothetheirinactivationandeventualcellwallrupture.
Doripenemisapprovedforthetreatmentofcomplicatedintra-aBDominalinfectionsandurinarytractinfections.Itisactiveagainstgram-positive,gram-negative,andanaerobicorganisms,andisstableagainstawidevarietyofb-lactamasesandrenaldehydropeptidases.[2,3]
Technicalinformation:
| ChemicalFormula: | C15H24N4O6S2.H2O | |
| CAS#: | 148016-81-3 | |
| MolecularWeight: | 438.52 | |
| Purity: | >99% | |
| Appearance: | White | |
| ChemicalName: | 1-AzABIcyclo[3.2.0]hept-2-ene-2-carboxylicacid,3-[[(3S,5S)-5-[[(aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-,hydrate | |
| Solubility: | Upto75mMinDMSO | |
| Synonyms: | Doripenem,Doribax |
ShippingCondition:Theproductisshippedinaglassvialatambienttemperature.
Storagecondition:Forlongershelflife,storesolidpowderat4oCdesiccated,orstoreDMSOsolutionat-20oC.
Reference:
| 1. | Patersonetal.,Doripenem.Clin.Infect.Dis.2009,49(2),291-298.PubmedID:19527173 |
| 2. | Matthewsetal.,Doripenemmonohydrate,abroad-spectrumcarbapenemantibiotic.Clin.Therapeutics,2009,31(1),42-63.PubmedID:19243706 |
| 3. | Greeretal.,Doripenem(Doribax):thenewestadditiontothecarbapenems.Proceedings,BaylorUniversityMedicalCenter,2008,21(3),337-341.PubmedID:18628935 |
SouthernBiotech/Goat Anti-Human Lambda-Alexa Fluor® 555/2070-32/1.0 mg
vectorlabs/Biotinylated Aleuria Aurantia Lectin (AAL)/B-1395/1 mg
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Mouse IgG)/PK-6102/1 kit
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Universal)/PK-6200/1 kit
vectorlabs/Unconjugated Musa Paradisiaca (Banana) Lectin (BanLec)/L-1410/5 mg
GiottoBiotech/Calmodulin N60D/5 mg/G02CLM60cn